The feeling (vedanā) of pain which is produced involuntarily on account of the fruition of Vedaniya (feeling-experiencing) Karma and the instrumental cause of disease etc.
svayameva samīpe bhavanamndīraṇākaraṇena vā samīpānayanaṃ tena nirvṛttā aupakramikī.(Prajñā 35.12 Vṛ Pa 557)
- Ābhyupagamikī Vedanā.