The Jaina Doctrine of Karma And The Science Of Genetics: Diseases Associated with Chromosomes

1.

1

3000

240

90%

(1) UROD Porphyria Cutanea tarda
(2) GBA Gaucher disease
(3) GLC1A Glaucoma
(4) HPC1 Prostate Cancer
(5) PS2 Alzheimer disease

2.

2

2500

240

95%

(1) ETM2 Essential tremor
(2) MS6 Colon Cancer
(3) PAX3 Wardenberg Syndrom

3.

3

1900

200

95%

(1) UHL Von Hippel Lindau
(2) MLH1 Colon Cancer
(3) SCLC1 Lung Cancer
(4) ETM1 Essential tremor

4.

4

1600

190

95%

(1) EVC Ellis-Van-Creveld
(2) HD Huntington disease
(3) FGFR3 Achondroplasia
(4) NRCPL Narcolepsy
(5) SNCA parkinson disease
(6) FOP Fibrodysplasia Ossificans progressiva

5.

5

1700

180

95%

(1) SRD5A1 Steroid 5-alpha reductase1
(2) CKN1 Cockayne syndrom
(3) SMN1 Spinal muscular atrophy
(4) Asthma
(5) DTD Diastrophic dysplasia

6.

6

1900

170

95%

(1) SCA1 Spinocerebellar ataxia
(2) HFE Hemo Chromatosis
(3) IDDM1 Diabetes
(4) CYP21A Congenital adrenal hyper plasia due to 21 hydroxylase dificiency
(5) EPM2A Epilepsy

7.

7

1800

150

95%

(1) GCK Diabetes
(2) ELN Williams syndrome
(3) CTFR fibrosis
(4) Pendrin Pendred syndrome
(5) Obesity

8.

8

1400

140

95%

(1) WRN Werner syndrome
(2) MYC Barkitt lymphoma

9.

9

1400

130

85%

(1) CDKN2 Malignant melanoma
(2) FRDA Friedrich's ataxia
(3) ABCI Tangier disease
(4) TSC1 Tuberoussclerosis
(5) ABL Chronic mycloid Leukemia

10.

10

1400

130

95%

(1) PAHX Refsum disease
(2) OAT Gyrate atrophy

11.

11

2000

130

95%

(1) HRAS Harvey Ras Oncogene
(2) IDDM2 Diabetes
(3) LQT Long QT syndrome
(4) VMD2 Best syndrome
(5) MEN1 multiple endocrine neoplasia
(6) ATM Ataxia telangiectasia.

12.

12

1600

130

95%

(1) PXR1 Zellweger syndrom
(2) PAH Phenylketonuria

13.

13

800

110

80%

(1) BRCA2 Breast Cancer
(2) CX 26 Autosomal recessive neurosensory deafness
(3) RB1 Retinoblastoma
(4) ATP7B Wilson disease

14.

14

1200

100

80%

(1) PS1 (AD3) Alzhimer disease
(2) SERPINA1 alpha-1-antitrypsin deficiency

15.

15

1200

100

80%

(1) SNRPN prader-willi syndrome
(2) UBE Angelman syndrome
(3) FBN1 Marfan syndrome
(4) HEXA Tay-sachs disease

16.

16

1300

90

85%

(1) HBA1, HBA2 Alpha thalassemia
(2) PKD1 Polycystic kidney disease
(3) FMF Femilial mediterranean fever
(4) Crohn's disease

17.

17

1600

80

95%

(1) PS3 Tumor suppressor protein
(2) CMT1A Charcot-marie-tooth syndrom
(3) BRCA1 Breast Cancer

18.

18

600

70

95%

(1) NPCI Niemann-pick disease
(2) DPC4 Pancteatic cancer

19.

19

1700

60

85%

(1) JAK2 Severe combined immunodeficiency
(2) BCKDHA Maple syrup urine disease
(3) DMPK Mytotonic dystrophy
(4) APOE Atherosclerosis

20.

20

900

60

90%

(1) ADA Severe combined immuno deficiency

21.

21

400

40

70%

(1) SOD1 Amylotrophic lateral sclerosis.
(2) APS1 Autoimmune polyglandular syndrome.

22.

22

800

40

70%

(1) SGLT1 Glucose galactase malabsorption.
(2) DGS Digcorge syndrome.
(3) NF2 Neurofibromatosis.
(4) BCR Chronic myeoloid leukemia.

X

X

1400

150

95%

(1) PIG-A Paroxysmal nocturnal hemoglobinuria.
(2) DMD Duchenne Muscular Dystrophy.
(3) ATP7A Menkes syndrome.
(4) COL4AS Alport syndrome.
(5) IL2RG X-linked Severe Combined Immunodeficiency (SCID).
(6) TNFSF5 Immunodeficiency with hyper 19m.
(7) HPRT1 Lesch-nyhan syndrome.
(8) FMR1 Fragile X syndrome.
(9) MEC P2 Rett syndrome.
(10) ALD Adrenoleukodystrophy.
(11) HEMA hemophilia A.

Y

Y

200

5

50%

(1) SRY Testes determining factor.

Total

23

34300

2935

-

92 types of diseases

Fig.39b